Effect of Adding Magnesium Oxide Nanoparticles on the Antimicrobial Activity of a Denture Soft Liner

Hoshang K. Abdel-Rahman; Salem A. Salem Al-Sammaraie

doi:10.25156/ptj.v10n2y2020.pp132-137

Authors

Hoshang K. Abdel-Rahman Department of Prosthodontic, College of Dentistry, Hawler Medical University, Erbil, Kurdistan Region, Iraq https://orcid.org/0000-0001-9025-3754
Salem A. Salem Al-Sammaraie Department of Prosthodontic, College of Dentistry, Hawler Medical University, Erbil, Kurdistan Region, Iraq https://orcid.org/0000-0002-3568-4743

DOI:

https://doi.org/10.25156/ptj.v10n2y2020.pp132-137

Keywords:

Soft liner, Nanoparticle, Candida albicans, Staphylococcus aureus, Biofilm

Abstract

Microbial growth and colonization are one of the disadvantages after the long-term use of denture soft liners. This study was aimed to evaluate the effect of the addition of magnesium oxide nanoparticles (MgONPs) on the antimicrobial activity of a denture soft liner. A total of 84 samples were prepared from a soft denture liner and divided into two groups, control group and test group to which 3% by weight of MgONPs were added, antimicrobial tests for Candida albicans, Staphylococcus aureus, and a mixture of the biofilm of both microorganisms were done, cell density count and adherence assay test was recorded before and after 6 months storage in distilled water. The results showed that the modified group performed a better antimicrobial activity compared to the control group, the addition of 3% of the nanofiller showed a significant reduction in the mean value of growth of both C. albicans, S. aureus, and the biofilm mixture (P < 0.05) before and after the storage period. In conclusion, the addition of 3% by weight of MgONPs to the denture soft liner significantly suppressed the growth of C. albicans, S. aureus up to 6 months.

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Effect of Adding Magnesium Oxide Nanoparticles on the Antimicrobial Activity of a Denture Soft Liner

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