Diagnostic Value of Thrombocytopenia in Helicobacter pylori Infection Among Pregnant and Non-pregnant Women in Erbil City

Authors

  • Najat Barwary Department of Medical Laboratory Technology,Health Technical College/ Erbil Polytechnic University
  • Saeed Ghulam Department of Microbiology, College of Medicine / Hawler Medical University.
  • Goran Othman Department of Medical Laboratory Technology,Health Technical College/ Erbil Polytechnic University

DOI:

https://doi.org/10.25156/ptj.2017.7.3.114

Keywords:

H. pylori, Thrombocytopenia, Pregnant women.

Abstract

Thrombocytopenia is one of the health problems that faced pregnant women. The formation of antibodies against some of viral and bacterial infection leads to molecular mimicry with the surface of platelets. Hence, it leads to thrombocytopenic purpura. In current study, 421 women including 388 pregnant and 33 non-pregnant women, aged between 18 - 44 years participated in this study. Complete blood count (CBC) and anti H. pylori tests were performed for all participants. A total number of seropositive women for anti H. pylori Ab test (IgG) was 253 (60.1%) including 237 pregnant women and 93 of them were with history of abortion. The results showed significant differences (p<0.000) in mean platelet count between seropositive results for Anti H. pylori Ab test (IgG) and women with seronegative results. Among 253 seropositive women, 199 (78.65%) of them have low platelet count, while only (4.76%) of seronegative women were thrombocytopenic. The cutoff of platelet count for thrombocytopenia set on (150,000 cell/cmm3). ROC analysis revealed good prognostic value of thrombocytopenia for H. pylori infection. This

finding concluded that thrombocytopenia can be one of biomarker for H pylori infection among pregnant women.

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Published

2017-09-01

How to Cite

Barwary, N., Ghulam, S. ., & Othman, G. (2017). Diagnostic Value of Thrombocytopenia in Helicobacter pylori Infection Among Pregnant and Non-pregnant Women in Erbil City. Polytechnic Journal, 7(3), 123-133. https://doi.org/10.25156/ptj.2017.7.3.114

Issue

Vol. 7 No. 3 (2017)

Section

Research Articles

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